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Mid-ventricular hypertrophic cardiomyopathy with apical aneurysm: a multimodality imaging case report

Pavel Martinez-Dominguez1,2, Manuel Horna-Noriega3, María José Santa-Ana-Bayona1

  • 1Departamento de Cardiología Nuclear, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México. Departamento de Cardiología Nuclear Instituto Nacional de Cardiología Ignacio Chávez Ciudad de México México.

Archivos Peruanos De Cardiologia Y Cirugia Cardiovascular
|May 16, 2025
PubMed

Insights

Mid-ventricular hypertrophic cardiomyopathy, a rare condition, can cause apical aneurysms and increase risks for cardiac arrest and sudden cardiac death. This case highlights diagnosis and management strategies for this challenging cardiomyopathy.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Genetics

Background:

  • Hypertrophic cardiomyopathy (HCM) is a primary myocardial disease.
  • Mid-ventricular HCM is a rare variant characterized by hypertrophy predominantly in the mid-ventricle.
  • Apical aneurysms can be a presenting feature of mid-ventricular HCM.

Observation:

  • A 41-year-old male presented with exertional dyspnea and syncope.
  • Multimodality imaging, including echocardiography and cardiac magnetic resonance, revealed mid-ventricular hypertrophy.
  • An apical aneurysm was identified in conjunction with the ventricular hypertrophy.

Findings:

  • The imaging findings confirmed the diagnosis of mid-ventricular hypertrophic cardiomyopathy with apical aneurysm.
  • This specific subtype of HCM is associated with a heightened risk of adverse cardiac events.
  • Potential complications include heart failure, thromboembolic events, cardiac arrest, and sudden cardiac death.

Implications:

  • Early recognition and diagnosis of mid-ventricular HCM with apical aneurysm are crucial.
  • Risk stratification and appropriate management, such as ICD implantation, are vital for preventing sudden cardiac death.
  • Further research into the pathophysiology and long-term outcomes of this rare condition is warranted.

Keywords:
Defibrillators, ImplantableEchocardiographyHypertrophy, Left Ventricular

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