Related Experiment Video
Updated: May 17, 2025
15:49
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
31.6K
Variation in Proximal Sessile Serrated Lesion Detection Rates During Non-screening Colonoscopies.
Mo Thoufeeq1, Vikram Mohanan2, Nilanga Nishad1
1Gastroenterology, Sheffield Teaching Hospitals National Health Service (NHS) Foundation Trust, Sheffield, GBR.
Cureus
|May 16, 2025
Summary
Sessile serrated lesions (SSLs) are precursors to colon cancer. This study found wide variability in their detection rates among endoscopists, suggesting SSL detection should be a key performance indicator.
Area of Science:
- Gastroenterology
- Endoscopy
- Oncology
Background:
- Proximal sessile serrated lesions (PSSL) are increasingly recognized as significant precursors of interval colon cancer.
- Assessing PSSL detection rates is crucial for improving colon cancer prevention.
Purpose of the Study:
- To evaluate PSSL detection rates during non-screening colonoscopies.
- To determine associations between PSSL detection rate and established colonoscopy key performance indicators (KPIs).
Main Methods:
- Retrospective collection of data from 2956 non-screening colonoscopies.
- Analysis of endoscopists' KPIs: polyp detection rate (PDR), cecal intubation rate (CIR), and colonoscopy withdrawal time (CWT).
- Statistical assessment of associations using Spearman's test.
Main Results:
- Mean PSSL detection rate was 0.7%, with significant inter-endoscopist variability (0-6.5%).
- PSSL detection rate positively correlated with colonoscopy withdrawal time (CWT).
- No significant correlation found between PSSL detection rate and PDR or CIR.
Conclusions:
- Wide variability in PSSL detection suggests high miss rates, even with adherence to national KPI benchmarks.
- PSSL detection rate should be considered an independent key performance indicator for colonoscopy quality.
- Improved PSSL detection is essential for reducing interval colon cancer.
Keywords:
colonoscopy surveillancecolorectal cancersessile serrated adenomasessile serrated lesioncolonoscopyMore Related Videos
Related Concept Videos
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
34
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
34
01:25Assessment of the Rectum and Anus
117
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
117
01:25Endoscopic Procedures II: Colonoscopy
37
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
37
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
31
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
31