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Cytomegalovirus-Associated Septic Shock Leading to Disseminated Intravascular Coagulation
Brandon Weissman1, Sumi Singh2, Taher Sbitli2
1Otolaryngology, Lake Erie College of Osteopathic Medicine, Elmira, USA.
Cureus
|May 16, 2025
Summary
This case study shows a rare instance of Cytomegalovirus (CMV) causing septic shock and disseminated intravascular coagulation (DIC) in an immunosuppressed patient. Early diagnosis and aggressive treatment with ganciclovir and supportive care led to recovery.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- Cytomegalovirus (CMV) infections pose significant risks, often leading to severe complications in immunocompromised individuals.
- Patients with chronic kidney disease, diabetes mellitus, and other immunosuppressive conditions are particularly vulnerable to severe CMV manifestations.
- The case involves a 58-year-old woman with multiple comorbidities presenting with symptoms initially misdiagnosed.

