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Prolonged life-threatening anaphylaxis to Floseal during partial nephrectomy: A case report
George McClintock1, David Frishling2, Yen Lam3
1Department of Urology, Chris O'Brien Lifehouse Hospital, Camperdown, NSW, Australia.
Current Urology
|May 16, 2025
Summary
This case report details the first adult Floseal Hemostatic Matrix allergy, presenting as anaphylaxis during a partial nephrectomy. Allergy testing confirmed a gelatin matrix allergy, highlighting the need to consider Floseal anaphylaxis in post-operative cardiovascular collapse.
Area of Science:
- Anesthesiology
- Nephrology
- Immunology
Background:
- Floseal Hemostatic Matrix is a widely used topical hemostatic agent.
- It is frequently applied to the renal bed during partial nephrectomy procedures.
- Adverse reactions to Floseal are rarely reported in adult patients.
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