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Updated: May 17, 2025

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Where Adults With Heart Failure Die: Insights From the CDC-WONDER Database.
Farman Ali1, Shaaf Ahmad2, Aman Ullah3
1Department of Internal Medicine, Corewell Health Dearborn Hospital, Dearborn, MI (F. Ali, T.J.B.).
Deaths at home for heart failure (HF) patients nearly doubled between 1999 and 2023. This study analyzed HF mortality locations, revealing significant shifts and demographic disparities in end-of-life care settings.
Area of Science:
- Cardiology
- Public Health
- Gerontology
Background:
- Heart failure (HF) is a leading cause of mortality and significant healthcare expenditure.
- Integrating palliative care into HF management is increasingly emphasized.
- Data on end-of-life care locations for HF patients remain limited.
Purpose of the Study:
- To analyze the location and circumstances of death among adults with heart failure in the United States.
- To identify trends in where heart failure patients die over time.
- To examine demographic factors associated with death location in heart failure.
Main Methods:
- Analysis of mortality data from 1999-2023 for individuals aged 20+ with HF as the cause of death.
- Categorization of death locations: emergency room, hospice/nursing home, inpatient facility, or home.
- Multinomial logistic regression to assess associations between demographics and death location.
Main Results:
- Heart failure mortality rates declined until 2010, then increased by 2023.
- Deaths at home nearly doubled from 18.41% in 1999 to 33.47% in 2023.
- Hospice/nursing home deaths peaked in 2017 and declined by 2023; young adults showed higher inpatient deaths.
- Men, White individuals, and those in large metropolitan areas were more likely to die in medical facilities.
Conclusions:
- Significant shifts in end-of-life locations for heart failure patients observed, with a notable rise in home deaths.
- The recent decline in hospice/nursing home deaths warrants further investigation into potential barriers.
- Sociodemographic factors significantly influence disparities in heart failure death locations, requiring further research.
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