Vulvar basal cell carcinoma treated with Mohs micrographic surgery: a case series and systematic review

Basal cell carcinoma (BCC) is the most common type of skin cancer. Vulvar BCC accounts for < 1% of all BCCs but can be difficult to manage due to its functionally and cosmetically relevant anatomical location. Mohs micrographic surgery (MMS) is a tissue-sparing technique that ensures complete margin analysis, minimizing recurrence while preserving healthy tissue. In this study, we systematically reviewed the literature, searching for cases of vulvar BCC treated with MMS. Eight articles representing 17 cases of vulvar BCC treated with MMS have been published, and we added three extra cases of our own experience. The present study highlights the relevance of including BCC in the differential diagnosis of vulvar dermatosis and the key role of MMS in the vulvar region, where tissue sparing and preservation of functionality are vital.