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Updated: Oct 9, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Alternative explanations for normal variability in antithrombin-III levels
Abstract:
Data collected in a study of ATIII deficiency also suggested familial variability of blood clotting times amongst genotypically normal individuals. A study of this variability under a variety of models demonstrates a clear age effect and within sibship similarity. There is also a clear parental effect, which could be either environmental or genetic. Even when parental effects are taken into account there remains some excess similarity between sibs, but the increase in log-likelihood provided by this component is no longer highly significant.
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