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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
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Male Sexual Disorders: Infertility and Low Libido.

Roderick Clark1, Roland Newman2, Benjamin Silverberg3

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Infertility affects couples trying to conceive, with evaluation including semen analysis and assessment for underlying conditions. Low male libido requires diagnosis and can be treated with testosterone replacement therapy when deficiency is present.

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Area of Science:

  • Reproductive Endocrinology
  • Men's Health
  • Sexual Medicine

Background:

  • Infertility is defined as the inability to conceive after 12 months of regular, unprotected intercourse, with diagnostic timelines varying by female age.
  • Male infertility evaluation involves assessing medical conditions and semen analysis, while unexplained infertility affects approximately 25% of couples.
  • Low libido in men is often underdiagnosed and requires assessment of distress, contributing factors, and sexual health goals.

Purpose of the Study:

  • To provide a comprehensive overview of infertility diagnosis and management.
  • To highlight the importance of evaluating male infertility and unexplained cases.
  • To discuss the diagnosis and management of low libido in men, including the role of testosterone deficiency.

Main Methods:

  • Review of established definitions and diagnostic criteria for infertility.
  • Discussion of recommended evaluation protocols for male infertility, including semen analysis.
  • Exploration of diagnostic tools for low libido, such as the Sexual Desire Inventory-2, and consideration of contributing factors.

Main Results:

  • Infertility diagnosis is time-sensitive, with earlier consideration for women over 35.
  • Assisted reproductive technologies offer solutions for various infertility cases, including unexplained infertility.
  • Low libido diagnosis hinges on patient distress, and potential treatments include addressing underlying medical conditions and testosterone replacement therapy for deficiency.

Conclusions:

  • Timely and thorough evaluation is crucial for both infertility and low libido.
  • A multifactorial approach is necessary for managing male infertility and low sexual desire.
  • Testosterone replacement therapy is a viable option for men with confirmed testosterone deficiency and low libido.