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Updated: Jun 16, 2026

Protein Target Prediction and Validation of Small Molecule Compound
Published on: February 23, 2024
Predicting Protein Function in the AI and Big Data Era
Riccardo Percudani1, Carlo De Rito1
1Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.
Abstract:
It is an exciting time for researchers working to link proteins to their functions. Most techniques for extracting functional information from genomic sequences were developed several years ago, with major progress driven by the availability of big data. Now, groundbreaking advances in deep-learning and AI-based methods have enriched protein databases with three-dimensional information and offer the potential to predict biochemical properties and biomolecular interactions, providing key functional insights. This progress is expected to increase the proportion of functionally bright proteins in databases and deepen our understanding of life at the molecular level.
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