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Published on: April 14, 2014
Ocular manifestations and treatment progress of Parry-Romberg syndrome
Dengfeng Zhang1,2, Shuting Huang1,2, Xin Zhang1,2
1Department of Ophthalmology, Chengdu Integrated TCM & Western Medicine Hospital /Chengdu First People's Hospital/Chengdu University of Traditional Chinese Medicine Affiliated Integrated TCM & Western Medicine Hospital, No.18 Wanxiang North Road, Chengdu, Sichuan Province, China.
Purposes:
Parry-Romberg syndrome is a rare degenerative disease. This article focuses on the ocular aspects of Parry-Romberg syndrome to help diagnose and further explore more effective treatments.
Methods:
A combined systematic search of PubMed electronic database by using Boolean operators AND and OR was conducted, choosing the following keywords: "Parry-Romberg syndrome", "Progressive hemifacial atrophy", "eye", "oculus", "ophthalmic", "ophthalmologic", "ophthalmology" and "global", etc. After the initial screening of these articles, repetitive literatures were excluded.
Results:
69 articles were selected. This study introduces the ocular manifestations, possible pathogenesis, and treatment progress of Parry-Romberg syndrome.
Conclusion:
There is currently no clear pathogenesis and effective treatment for Parry-Romberg syndrome. Understanding its pathological mechanism in the context of autoimmune etiology and exploring its phenotype-genotype correlation may help find more valuable treatments.
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