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Related Experiment Video

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Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
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Published on: February 13, 2011

Accelerated deep learning-based function assessment in cardiovascular magnetic resonance.

Domenico De Santis1, Federica Fanelli1, Luca Pugliese1

  • 1Department of Medical-Surgical Sciences and Translational Medicine, School of Medicine and Psychology, Sapienza - University of Rome, Sant'Andrea University Hospital, Via Di Grottarossa, 1035-1039, 00189, Rome, Italy.

La Radiologia Medica
|May 17, 2025
PubMed
Summary
This summary is machine-generated.

Deep learning (DL) cine sequences provide fast and accurate quantification of left and right ventricular parameters in cardiovascular magnetic resonance (CMR), matching the image quality of conventional balanced steady-state free precession (bSSFP) sequences.

Keywords:
Artificial intelligenceCardiac MRICardiac functionCardiovascular magnetic resonanceDeep learningFast imaging

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Area of Science:

  • Cardiovascular Imaging
  • Artificial Intelligence in Medicine
  • Medical Diagnostics

Background:

  • Cardiovascular magnetic resonance (CMR) is crucial for assessing cardiac function.
  • Conventional balanced steady-state free precession (bSSFP) cine sequences are standard for CMR but can be time-consuming.
  • Deep learning (DL) offers potential for faster and efficient image acquisition and analysis.

Purpose of the Study:

  • To compare the diagnostic accuracy and image quality of DL cine sequences against conventional bSSFP cine sequences for left ventricular (LV) and right ventricular (RV) parameter quantification in CMR.
  • To evaluate the speed of DL cine sequences compared to bSSFP sequences.

Main Methods:

  • Prospective inclusion of patients undergoing clinically indicated CMR.
  • Segmentation of LV and RV from both bSSFP and DL cine sequences.
  • Calculation of LV and RV volumetric and functional parameters (EDV, ESV, SV, EF, LV mass).
  • Comparison of parameters using statistical tests and Bland-Altman analysis for agreement.
  • Assessment of image quality by two readers using a 5-point Likert scale.

Main Results:

  • No significant differences in LV and RV parameters were found between DL cine and bSSFP sequences (P ≥ .176).
  • DL cine sequences were significantly faster (1.35 min) than bSSFP sequences (2.83 min) (P < .001).
  • Strong agreement was observed between DL cine and bSSFP, with acceptable limits of agreement for end-systolic volume, stroke volume, and end-diastolic volume.
  • Overall image quality was comparable, though endocardial edge definition was slightly lower for DL cine.

Conclusions:

  • Deep learning cine sequences enable rapid and accurate quantification of LV and RV parameters in CMR.
  • DL cine demonstrates comparable diagnostic accuracy and overall image quality to conventional bSSFP sequences.
  • DL cine represents a promising advancement for efficient cardiovascular magnetic resonance imaging.