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Updated: May 20, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Development of male contraceptives is critical for women's health†
1School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, WA, United States.
Abstract:
Despite decades of advancement in reproductive medicine, the development of effective, reversible male contraceptives remains strikingly underfunded and underprioritized. This neglect has direct consequences for women, who disproportionately bear the burden of preventing pregnancy and managing the outcomes when contraception fails or is unavailable. Approximately half of all pregnancies globally are unintended, and the lack of male contraceptive options contributes substantially to this statistic. In this commentary, I argue that male contraceptive development should be recognized as an essential component of women's health research and policy-on par with gynecological and maternal health concerns. Without access to contraceptives for men, it is women-and by extension, their children and families-who ultimately bear the physical, emotional, and economic consequences of unintended pregnancy. Reproductive responsibility must be equitably shared, and that shift requires urgent investment in male contraceptive research.
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