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Updated: May 20, 2025
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Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
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Construction of polymethine chain-modified pentamethylene cyanine dyes for G-quadruplex imaging in live cells
Li Guan1, Jun Li1, Yanyan Zhou1
1School of Chemistry and Chemical Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, P. R. China. guanli0317@163.com.
Chemical Communications (Cambridge, England)
|May 19, 2025
Abstract:
Here, a supramolecular strategy that relies on the G-quadruplex DNA recognition-driven disaggregation of pentamethylene cyanine Cy5-ph-H aggregates is outlined, which can turn on its fluorescence and be used to visualize G-quadruplex DNA in living cells and highly target mitochondria.
