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Elevated Dehydroepiandrosterone Sulfate Levels in 2 Patients With Prolactinomas: An Underrecognized Association
Joseph Arguinchona1, Aditi Kumar1, Divya Yogi-Morren2
1Department of Endocrinology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
JCEM Case Reports
|May 19, 2025
Summary
Hyperprolactinemia, a condition of excess prolactin, can be linked to elevated dehydroepiandrosterone sulfate (DHEA-S) levels. Treating the underlying prolactinoma with cabergoline normalized DHEA-S in two male patients.
Area of Science:
- Endocrinology
- Reproductive Endocrinology
- Neuroendocrinology
Background:
- Adrenal androgen production is mainly regulated by ACTH.
- A less common association exists between hyperprolactinemia and elevated dehydroepiandrosterone sulfate (DHEA-S).
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