Related Experiment Video
Updated: May 21, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Isolated Skin Metastasis From Papillary Thyroid Carcinoma: A Rare Presentation
1Community Health Partners, Fresno, CA 93720, USA.
Abstract:
Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy and is often characterized by a high rate of regional lymph node involvement. However, distant metastasis is uncommon, and cutaneous metastases are particularly rare, occurring in fewer than 0.1% of cases. This report presents an unusual case of isolated skin metastasis as the first manifestation of distant spread in PTC. The case highlights the diagnostic challenges associated with this rare presentation, explores potential mechanisms underlying cutaneous dissemination, and underscores the significance of a multidisciplinary approach to management. The findings emphasize the importance of long-term surveillance and meticulous pathological evaluation in patients with PTC, particularly in cases with atypical metastatic patterns.
More Related Videos
09:14Isolation of Papillary and Reticular Fibroblasts from Human Skin by Fluorescence-activated Cell Sorting
Published on: May 7, 2019
04:01Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...