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Updated: May 21, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Synthesis of a Novel 1,3,4-Oxadiazole Derivative with Piperazine and Phenoxypropanol Functionalities
Deepak Kumar1,2, Suryakanta Dalai2, Girish Chandra Sharma1
1Department of Applied Sciences, Chemistry, NIMS University, Jaipur 303121, India.
Abstract:
Synthesis of novel heterocyclic derivatives of 1-amino-3-(3-(5-((4-phenylpiperazin-1-yl)methyl)-1,3,4-oxadiazol-3-yl)phenoxy)propan-2-ol is focused on specific piperazine and piperidine derivatives of 1,3,4-oxadiazole. These compounds are a distinguished motif for biological studies. An effective piperazine and piperidine derivatives methodology on 1,3,4,-oxadiazole substrates has been developed. This pathway along with good yields and clean reactions has a broad substrate scope. This pathway provides new biologically useful moieties that can further be investigated for their applicability.
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