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Clot in transit in a patient with massive pulmonary embolism: A case report of successful catheter directed

Patrick C Magnus1, Stephanie Cull2

  • 1Concord Hospital Cardiovascular Institute, Concord, NH, United States of America.

Respiratory Medicine Case Reports
|May 19, 2025
PubMed

Keywords:
Clot-in-transitHigh risk pulmonary embolism

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After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
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