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Related Experiment Videos

Nutrition and prostate cancer: a case-control study.

M Y Heshmat, L Kaul, J Kovi

    The Prostate
    |January 1, 1985
    PubMed
    Summary

    Higher intake of proteins, fats, and vitamin A in middle age was linked to increased prostate cancer risk in Black men. This suggests dietary factors may influence cancer development during younger years.

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    Area of Science:

    • Epidemiology
    • Nutritional Science
    • Oncology

    Background:

    • Prostate cancer disproportionately affects Black men.
    • Dietary factors are implicated in cancer development.
    • Specific nutrient associations require further investigation.

    Purpose of the Study:

    • To investigate the association between nutrient intake and prostate cancer risk in Black men.
    • To explore potential dietary risk factors during different age periods.

    Main Methods:

    • A case-control study involving 181 Black prostate cancer patients and 181 matched controls.
    • Personal interviews collected dietary consumption data for 18 nutrients.
    • Nutrient intake was assessed per 1,000 calories for age periods 30-49 and 50+ years.

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    Main Results:

    • Increased intake of proteins, total fat, saturated fat, oleic acid, and vitamin A during ages 30-49 was associated with enhanced prostate cancer risk.
    • Vitamin A showed a highly significant association, while others approached statistical significance.
    • No specific age period was mentioned for controls.

    Conclusions:

    • Dietary patterns, particularly high intake of certain fats and vitamin A in middle age, may increase prostate cancer risk in Black men.
    • A potential mechanism involving the zinc-retinol binding protein-vitamin A axis is proposed.