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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Updated: May 21, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
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AI-assisted diffuse correlation tomography for identifying breast cancer.

Ruizhi Zhang1, Jianju Lu2, Wenqi Di1

  • 1North University of China, State Key Laboratory of Dynamic Measurement Technology, Taiyuan, China.

Journal of Biomedical Optics
|May 19, 2025
PubMed
Summary

Artificial intelligence (AI)-assisted diffuse correlation tomography (DCT) accurately distinguishes between benign and malignant breast lesions at 97% accuracy. This technique shows promise for early breast cancer diagnosis and treatment monitoring by assessing microvascular blood flow.

Keywords:
artificial intelligencebreast cancerclinical imagingdiagnosismicrovascular blood flow

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Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Oncology

Background:

  • Diffuse correlation tomography (DCT) is an emerging noninvasive technique for measuring breast microvascular blood flow.
  • Validation of DCT for differentiating benign and malignant breast lesions is limited due to instrumentation and algorithmic challenges.

Purpose of the Study:

  • To develop and validate an AI-assisted DCT system for classifying breast lesions.
  • To assess the performance of AI models in analyzing DCT-derived blood flow data for lesion characterization.

Main Methods:

  • An AI-assisted DCT system was developed using a novel source-detector array and image reconstruction algorithm.
  • DCT images were acquired from 61 female patients.
  • AI models were trained using blood flow images as feature parameters or global inputs for lesion classification.

Main Results:

  • DCT measurements demonstrated stability in healthy subjects through longitudinal monitoring.
  • AI-assisted DCT achieved 97% accuracy in distinguishing between benign and malignant breast lesions.
  • The system effectively identified functional abnormalities linked to metabolic demands in breast diseases.

Conclusions:

  • AI-assisted DCT shows significant potential for the early diagnosis of breast cancer.
  • This technique can aid in timely therapeutic assessment by detecting functional changes before significant tumor or vascular network development.
  • The study highlights the capability of AI-assisted DCT in characterizing breast lesions noninvasively.