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Updated: May 21, 2025

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases

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Published on: November 8, 2024

PATHOMORPHOLOGY OF VERRUCAE: A CLINICOPATHOLOGIC STUDY.

I Emmanuel^1,2, P O Akpa^1,2, B V Kwaghe¹

¹Department of Anatomic Pathology and Forensic Medicine, Jos University Teaching Hospital, Nigeria, Jos, Plateau State, Nigeria.

Annals of Ibadan Postgraduate Medicine

|May 19, 2025

Summary

This study found that warts (verrucae) are most common in the anogenital region, affecting adults aged 30-49, particularly females. Early vaccination against Human Papilloma virus is recommended to reduce incidence.

Keywords:

Anus Cutaneous Genital.Verrucae,Warts

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Area of Science:

Dermatology
Pathology
Epidemiology

Background:

Verrucae, caused by Human Papilloma virus (HPV), are common skin lesions affecting 10% of the global population.
This study focuses on the clinicopathological characteristics of histologically diagnosed warts.

Purpose of the Study:

To analyze the clinicopathology of verrucae diagnosed at Jos University Teaching Hospital.
To identify demographic and clinical patterns of wart presentation.

Main Methods:

A descriptive study of all histologically diagnosed verrucae cases from 2013-2022.
Inclusion criteria: patients with histological diagnosis of verrucae and adequate data.
Exclusion criteria: inadequate biodata, clinical information, or missing samples.

Main Results:

61 cases of verrucae were analyzed, with a female predominance (54.1%).
The most affected age group was 30-49 years.
Anogenital warts (62.3%) were more common than cutaneous warts (37.7%), with the vulva being the most frequent site.
Cosmesis (84.4%) was the predominant reason for clinical presentation, followed by bleeding, pain, and itching.

Conclusions:

Warts are prevalent in the anogenital region, third and fourth decades of life, and in females.
Clinical presentations include bleeding, pain, itching, and cosmetic concerns.
Widespread vaccination against HPV is recommended to decrease the incidence of warts.