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PATHOMORPHOLOGY OF VERRUCAE: A CLINICOPATHOLOGIC STUDY.
I Emmanuel1,2, P O Akpa1,2, B V Kwaghe1
1Department of Anatomic Pathology and Forensic Medicine, Jos University Teaching Hospital, Nigeria, Jos, Plateau State, Nigeria.
Annals of Ibadan Postgraduate Medicine
|May 19, 2025
Summary
This study found that warts (verrucae) are most common in the anogenital region, affecting adults aged 30-49, particularly females. Early vaccination against Human Papilloma virus is recommended to reduce incidence.
Area of Science:
- Dermatology
- Pathology
- Epidemiology
Background:
- Verrucae, caused by Human Papilloma virus (HPV), are common skin lesions affecting 10% of the global population.
- This study focuses on the clinicopathological characteristics of histologically diagnosed warts.
Purpose of the Study:
- To analyze the clinicopathology of verrucae diagnosed at Jos University Teaching Hospital.
- To identify demographic and clinical patterns of wart presentation.
Main Methods:
- A descriptive study of all histologically diagnosed verrucae cases from 2013-2022.
- Inclusion criteria: patients with histological diagnosis of verrucae and adequate data.
- Exclusion criteria: inadequate biodata, clinical information, or missing samples.
Main Results:
- 61 cases of verrucae were analyzed, with a female predominance (54.1%).
- The most affected age group was 30-49 years.
- Anogenital warts (62.3%) were more common than cutaneous warts (37.7%), with the vulva being the most frequent site.
- Cosmesis (84.4%) was the predominant reason for clinical presentation, followed by bleeding, pain, and itching.
Conclusions:
- Warts are prevalent in the anogenital region, third and fourth decades of life, and in females.
- Clinical presentations include bleeding, pain, itching, and cosmetic concerns.
- Widespread vaccination against HPV is recommended to decrease the incidence of warts.
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