THE PLASMA CONCENTRATIONS OF ESSENTIAL TRACE ELEMENTS IN WOMEN WITH CANCER OF BREAST- OR CERVIX
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View abstract on PubMed
Summary
This summary is machine-generated.Plasma levels of iron and copper are significantly lower in women with breast or cervical cancer. Trace element levels, including zinc and selenium, also differ between cancer types, suggesting tailored supplementation may be beneficial.
Area Of Science
- Oncology
- Biochemistry
- Trace Element Analysis
Background
- Trace element derangements are linked to systemic inflammation and oxidative stress in carcinogenesis.
- Altered levels of essential metals may play a role in cancer development and progression.
Purpose Of The Study
- To investigate plasma trace element concentrations in female patients diagnosed with breast or cervical cancer.
- To compare trace element levels between cancer patients and a healthy control group.
Main Methods
- Plasma samples from 30 breast cancer patients, 30 cervical cancer patients, and 30 controls were analyzed.
- Concentrations of zinc (Zn), iron (Fe), selenium (Se), and copper (Cu) were measured using Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES).
Main Results
- Significantly reduced plasma levels of iron (Fe) and copper (Cu) were observed in both breast and cervical cancer patients compared to controls.
- Plasma concentrations of Fe, Cu, zinc (Zn), and selenium (Se) were lower in breast cancer patients, and stage 2 cervical cancer patients, compared to cervical cancer patients.
Conclusions
- Blood metal levels vary significantly across different cancer types.
- This supports the need for individualized trace element supplementation strategies in cancer therapy.
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