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Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
Bidirectional association between depression and cognition in Chinese middle-aged and older women: a 10-year
Xiaoxu Jiang1, Zheng Jiang2,3
1Maternal and Child Health Development Research Center, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, China.
Background:
Women's health is an important issue worldwide, and as the population is aging, the health of middle-aged and older women is becoming increasingly vital. Although many studies have examined the relationship between cognition and depression, few studies have been conducted specifically with middle-aged and older women. This study used a longitudinal approach to examine the bidirectional relationship between cognition and depression in middle-aged and older women.
Methods:
The study used three waves (2011, 2015, and 2020) of data from the China Health and Retirement Longitudinal Study (CHARLS), enrolling a total of 4,618 middle-aged and older women aged over 45 years. Participants' general demographic characteristics were analyzed descriptively, and changes in study variables were measured using repeated-measures analysis of variance. Generalized estimating equation (GEE) and cross-lagged models were used to investigate the longitudinal relationship between depression and cognition.
Results:
The results of the GEE and cross-lagged models revealed that previous cognitive problems lead to future depression and prior depressive conditions affect subsequent cognition.
Conclusions:
There is a bidirectional relationship between depression and cognition in middle-aged and older women over time. More clinical mechanisms need to be explored in the future.
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