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Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
Mechanisms of Membrane-bending01:15

Mechanisms of Membrane-bending

The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
Cell Migration01:19

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Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and regeneration, immune response, and metastasis. Cells migrate in response to chemical or mechanical signals generated by specific organs or tissues. The overall mechanism includes three steps - polarization, protrusion, and release. Polarization involves the formation of a distinct cell front and rear, which determines the direction of movement.
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
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Mechanism of Lamellipodia Formation01:31

Mechanism of Lamellipodia Formation

Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
Types of Membrane Protrusions01:28

Types of Membrane Protrusions

The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These membrane protrusions are a result of cytoskeletal rearrangement. The most  widely observed cell protrusions include lamellipodia, pseudopodia, filopodia, microvilli, invadopodia, and podosomes. These protrusions can be of two types — static or dynamic.
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Capillarity-induced fold localization in film-substrate systems.

So Nagashima1, Rikuto Ota1, Seishiro Matsubara1

  • 1Department of Mechanical Systems Engineering, Nagoya University, Nagoya 464-8603, Japan.

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|May 19, 2025
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Summary

Surface instability and elastocapillarity drive fold localization in thin films. High-aspect-ratio wrinkles enable channel formation, with reversible control via strain adjustment for novel applications.

Keywords:
elastocapillarityfoldsurface instabilitythin filmwater dropletwrinkle

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Area of Science:

  • Mechanics of Materials
  • Surface Science
  • Biophysics

Background:

  • Surface instability and elastocapillarity are fundamental in biological and engineered systems.
  • Understanding fold localization is key to controlling surface morphology.

Purpose of the Study:

  • Investigate capillarity-induced fold localization in film-substrate systems.
  • Analyze the influence of wrinkle aspect ratio on fold morphology.
  • Explore reversible control of morphological transitions.

Main Methods:

  • Experimental investigation of film-substrate systems.
  • Finite element simulations for mechanical analysis.
  • Water droplet deposition to induce surface changes.

Main Results:

  • Globally ordered wrinkles transform into localized folds upon water droplet deposition.
  • Fold morphology and dimensions are dictated by initial wrinkle aspect ratio.
  • High-aspect-ratio wrinkles promote spontaneous formation of subsurface channels.
  • Morphological transitions between wrinkles and folds are reversible with strain adjustment.

Conclusions:

  • Established a framework for understanding surface instability and elastocapillarity.
  • Demonstrated the role of wrinkle geometry in fold localization and channel formation.
  • Provided design principles for functional surfaces and devices, including fold nanochannels and graphene oxide folding.