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Updated: May 20, 2025
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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 9, 2010
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DNA-programmed nanomaterials: advancing biosensing, bioimaging, and therapeutic applications.
Hongyan Zhang1, Hexv Niu1, Zhe Hao1
1Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, P. R. China. zhangrz2019@tju.edu.cn.
Chemical Communications (Cambridge, England)
|May 19, 2025
Summary
DNA-programmed nanomaterials use DNA
Area of Science:
- Convergence of nanotechnology and molecular biology.
- Development of DNA-engineered nanomaterials.
Background:
- DNA offers programmability, molecular recognition, and biocompatibility.
- These properties enable precise design of nanostructures.
Purpose of the Study:
- To review construction and functionalization of DNA-conjugated nanomaterials and DNA-templated assemblies.
- To highlight their applications in biosensing, bioimaging, and therapeutic delivery.
- To discuss their roles in disease diagnosis and precision medicine.
Main Methods:
- Systematic exploration of DNA-conjugated nanomaterials (e.g., DNA-gold nanoparticles, DNA-upconversion nanoparticles, DNA-metal-organic frameworks).
- Review of DNA-templated assemblies (e.g., metal nanoclusters, quantum dots).
- Highlighting tailored physicochemical properties and dynamic responsiveness.
Main Results:
- Diverse DNA-engineered nanomaterials have been developed.
- These nanomaterials exhibit tailored properties and responsiveness.
- Applications demonstrated in biosensing, bioimaging, and therapeutic delivery.
Conclusions:
- DNA-programmed nanomaterials are crucial for early disease diagnosis and precision medicine.
- This review enhances understanding of current advancements.
- Future innovations in controllable assembly and biomedical applications are inspired.
