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Fluorescence-based Measurement of Store-operated Calcium Entry in Live Cells: from Cultured Cancer Cell to Skeletal Muscle Fiber
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Comparison of Phasic Store-Operated Calcium Entry in Rat Slow- and Fast-Twitch Muscle Fibers

Elena Lilliu1, Rocky Choi2, Karlheinz Hilber1

  • 1Center for Physiology and Pharmacology, Medical University of Vienna, Wien, Austria.

Acta Physiologica (Oxford, England)
|May 19, 2025
PubMed
Summary

Slow-twitch muscle fibers show higher sensitivity to store-operated calcium entry (SOCE) activation than fast-twitch fibers, despite releasing less calcium. This difference may enhance calcium homeostasis and disease resilience in slow-twitch muscle.

Keywords:
EC‐couplingcalciumskeletal muscleslow‐twitch musclestore‐operated calcium entry

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