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Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Clinical progress note: Pertussis
Samantha Hanna1, Nicole Samies2
1Division of Hospital Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
None:
Pertussis, commonly known as whooping cough, is a vaccine-preventable respiratory disease with rising incidence due to declining vaccination rates and waning immunity. The most severe disease course is seen in unvaccinated or incompletely vaccinated infants less than 2 months of age, accounting for the largest burden of hospitalization and death, but adolescents and adults play an important role in pertussis transmission and outbreaks. Prompt recognition and diagnosis remain critical for hospitalists in the management of pertussis disease and prevention.
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