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Rare rectal elastofibroma: diagnostic challenges and case report.

Chen-Xin Xiang^1,2, Yu Long^1,2, Yi-Ning Xiang³

¹Department of Colorectal Surgery, The Affiliated Hospital of Guizhou Medical University, No. 16 Beijing Road, Yunyan District, Guiyang, 550001, Guizhou, China.

Discover Oncology

|May 19, 2025

Summary

This summary is machine-generated.

Elastofibroma (EF) is a rare soft tissue tumor. This report details an uncommon rectal EF case, highlighting the need for histopathology and immunohistochemistry for accurate diagnosis.

Keywords:

Case report Elastofibroma Neuroendocrine tumors Rectum Special staining

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Area of Science:

Oncology
Pathology
Gastroenterology

Background:

Elastofibroma (EF) is a rare soft tissue tumor, typically found in the scapular region.
Rectal elastofibroma is exceptionally uncommon, presenting diagnostic challenges.

Purpose of the Study:

To report a rare case of rectal elastofibroma.
To emphasize the diagnostic difficulties and the importance of histopathological and immunohistochemical analysis in differentiating rectal EF from other spindle cell neoplasms.

Main Methods:

Case presentation of a 72-year-old female with rectal EF.
Definitive diagnosis confirmed via histopathology, immunohistochemistry, and special staining.

Main Results:

Histopathological and immunohistochemical analyses were crucial for definitive diagnosis.
Imaging findings were inconclusive, underscoring the need for specialized testing.

Conclusions:

Rectal elastofibroma is a rare entity requiring careful diagnostic consideration.
Histopathology and immunohistochemistry are essential for accurate diagnosis and differentiation from other spindle cell tumors, especially when imaging is ambiguous.