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Subject-Reported Satisfaction After Cell-Enriched Lipotransfer (CELT) for Lip Augmentation.

Sophia Diesch1, Konstantin Frank2, Vanessa Brébant2

  • 1Department of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany. sophia.diesch@ukr.de.

Aesthetic Plastic Surgery
|May 19, 2025
PubMed
Summary

The cell-enriched lipotransfer (CELT) method significantly improves patient satisfaction for lip augmentation compared to traditional fat grafting techniques. This natural approach offers superior results and higher patient contentment.

Keywords:
Autologous fat gratingCELTLip augmentationLipotransferLipsMesenchymal stem cellsStem cells

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Area of Science:

  • Plastic Surgery
  • Aesthetic Medicine
  • Regenerative Medicine

Background:

  • Lip augmentation is a popular cosmetic procedure, with full lips associated with youth and beauty.
  • Autologous fat grafting offers a natural alternative to temporary fillers.
  • The cell-enriched lipotransfer (CELT) method is an advanced technique for fat grafting.

Purpose of the Study:

  • To evaluate patient satisfaction with lip augmentation using the CELT technique.
  • To compare CELT with traditional fat preparation methods (sedimentation, filtration).
  • To assess the impact of patient demographics and injected volume on satisfaction.

Main Methods:

  • Retrospective chart review of lip augmentation patients.
  • Satisfaction assessed using the FACE-Q™ questionnaire.
  • Statistical analysis (Kruskal-Wallis, Pearson's correlation) of preparation method, volume, and demographics.

Main Results:

  • CELT significantly outperformed sedimentation/filtration in all satisfaction aspects (p < 0.001).
  • CELT improved lip shape, lower lip fullness, and Cupid's bow.
  • Gender, age, and injected volume influenced specific satisfaction outcomes.

Conclusions:

  • The CELT technique significantly enhances patient satisfaction in lip augmentation.
  • CELT offers superior fat retention and more natural outcomes than traditional methods.
  • Further research with objective volumetric measurements is recommended.