Ethanol and brain protein synthesis in the rat in vivo

The effect of ethanol consumption (27% of calories) for 21 days, concomitant with a low-protein (6% calories) or a normal protein diet (17.5% calories), on tyrosine kinetics and protein synthesis in the brain, was investigated. Ethanol consumption did not affect tyrosine concentrations in the plasma, cerebellum, forebrain or olfactory bulb but increased significantly the rate of synthesis of total mixed protein in the forebrain and cerebellum. This effect was observed in rats fed on both dietary protein regimes.