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Cannonball Lesions: A Case Report
1General Medicine, Austin Hospital, Heidelberg, AUS.
Cureus
|May 20, 2025
Summary
Cannonball lesions are round lung metastases often linked to specific cancers. This case highlights a rare instance of these lesions originating from hepatocellular carcinoma (HCC), expanding known associations.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Cannonball lesions are defined as multiple, well-circumscribed, spherical pulmonary nodules.
- These lesions typically represent hematogenous metastases from various primary malignancies.
- Commonly associated primary cancers include renal cell carcinoma, choriocarcinoma, colorectal cancer, and breast cancer.
Observation:
- This report details a unique case of cannonball pulmonary metastases.
- The metastases were identified in a patient with hepatocellular carcinoma (HCC).
Findings:
- Hepatocellular carcinoma (HCC) can manifest as cannonball lesions in the lungs.
- This finding expands the spectrum of primary tumors associated with this radiological pattern.
Implications:
- The identification of cannonball lesions necessitates a thorough investigation of potential primary sources.
- This case underscores the importance of considering less common primary malignancies, such as HCC, in the differential diagnosis of pulmonary metastases.
- Radiological findings of cannonball lesions may require broader oncological considerations.
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