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Influencing factors of false lumen thrombosis in type B aortic dissection: A single-center retrospective study
Qian-Hui Tang1, Han Yang1, Zhong Qin1
1Department of Vascular and Endovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.
Insights
Older age and shorter aortic dissection length are associated with false lumen thrombosis in patients with type B aortic dissection (TBAD). These findings help predict thrombosis risk in TBAD patients.
Area of Science:
- Vascular Surgery
- Cardiovascular Research
- Medical Imaging
Background:
- Type B aortic dissection (TBAD) is a serious condition affecting the aorta.
- False lumen thrombosis is a common complication in TBAD.
- Understanding factors associated with thrombosis is crucial for patient management.
Purpose of the Study:
- To identify factors associated with false lumen thrombosis in preoperative type B aortic dissection patients.
- To stratify risk for thrombosis based on patient demographics and dissection characteristics.
Main Methods:
- Retrospective evaluation of 285 TBAD patients (January 2008 - December 2017).
- Classification into patent, partial, and complete false lumen thrombosis groups.
- Univariate and logistic regression analyses to determine associated factors.
Main Results:
- Complete thrombosis group patients were older (59 ± 10 years) and had shorter dissection lengths (290 ± 101 mm) compared to other groups.
- Smaller primary tear size (OR 0.96), last tear size (OR 0.93), and fewer total tears (OR 0.87) were associated with partial thrombosis.
Conclusions:
- TBAD patients over 59 years old are more likely to have a thrombosed false lumen.
- Aortic dissection length under 290 mm is also a predictor of false lumen thrombosis.
- These factors can aid in predicting thrombosis risk in TBAD.
Objectives:
To evaluate the factors associated with false lumen thrombosis in preoperative type B aortic dissection (TBAD) patients.
Methods:
Between January 2008 and December 2017, TBAD patients were evaluated. Participants were divided into patent, partial thrombosis, and complete thrombosis groups according to the status of the false lumen. Univariate analysis and logistic regression analysis were used to identify the factors associated with false lumen thrombosis.
Results:
A total of 285 participants fulfilled our inclusion criteria. Patients in the complete thrombosis group were significantly older than those in the partial thrombosis and patent groups (59 ± 10 vs 53 ± 11 and 50 ± 11 years, respectively), and combined shorter dissection lengths (290 ± 101 vs 354 ± 92 and 351 ± 102 mm, respectively). The following factors were associated with partial thrombosis of the false lumen with an odds ratio (OR) <1: primary tear size (OR, 0.96; 95% confidence interval [CI], 0.93-0.99; p = 0.03), last tear size (OR, 0.93; 95% CI, 0.87-0.99; p = 0.04), and the total number of tears (OR, 0.87; 95% CI, 0.78-0.98; p = 0.02).
Conclusions:
TBAD patients older than 59 years or with aortic dissection lengths of less than 290 mm were more likely to have a thrombosed false lumen.
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