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A live birth after bilateral salpingo-oophorectomy for seromucinous borderline ovarian tumor
Kyota Saito1, Tatsuya Ishiguro1, Yukina Kitazawa1
1Department of Obstetrics and Gynecology, Niigata University Medical and Dental Hospital, Niigata, Japan.
Abstract:
Borderline ovarian tumors primarily affect younger women and are associated with favorable prognosis, making fertility-sparing surgery a viable option. However, owing to recurrence and malignant transformation risks, careful monitoring is required. Seromucinous borderline ovarian tumors, a rare subtype that is often associated with endometriosis, lack standardized guidelines for fertility-sparing surgery or infertility management following bilateral salpingo-oophorectomy with uterine preservation. We present a case of bilateral seromucinous borderline ovarian tumors stage IC3 managed with bilateral salpingo-oophorectomy, without observed recurrence, resulting in a live birth after frozen-thawed embryo transfer using embryos preserved before surgery. This case highlights the feasibility of bilateral salpingo-oophorectomy with uterine preservation and hormone replacement therapy-assisted frozen-thawed embryo transfer for seromucinous borderline ovarian tumors, emphasizing the importance of long-term surveillance and multidisciplinary management. Further research is required to establish evidence-based guidelines for seromucinous borderline ovarian tumor treatment and infertility care post-bilateral salpingo-oophorectomy.
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