Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Cardiac Implantable Electronic Devices Remote Programming.

Circulation. Arrhythmia and electrophysiology·2026
Same author

Catheter ablation of atrial fibrillation in transthyretin and light-chain cardiac amyloidosis: results from the multicentre AMYL-AF study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Wideband black- and bright-blood late gadolinium enhancement imaging in patients with implantable cardiac devices at 1.5 T for improved visualization and localization of myocardial injury.

European heart journal. Imaging methods and practice·2026
Same author

Ablation of Persistent Atrial Fibrillation Using a Dual-Energy Contact Force-sensing Catheter: Topography of Pulsed Field Mediated Symptoms and New Safety Challenges.

Circulation. Arrhythmia and electrophysiology·2026
Same author

Role of interatrial connection ablation in re-entry dynamics: an in silico evaluation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

[Pacemakers and cardiac resynchronization therapy : recent advances].

Revue medicale suisse·2026

Related Experiment Video

Updated: May 23, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.2K

Marshall-Plan Ablation Strategy Versus Pulmonary Vein Isolation in Persistent AF: A Randomized Controlled Trial.

Nicolas Derval1,2, Romain Tixier1,2, Josselin Duchateau1,2

  • 1IHU Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, France (N.D., R.T., J.D., X.B., R.C., B.B., M.A., M.Y., C.K., C.M., C.A., F.S., M. Hocini, P.J., M. Haïssaguerre, T.P.).

Circulation. Arrhythmia and Electrophysiology
|May 20, 2025
PubMed
Summary

The Marshall-Plan strategy, including pulmonary vein isolation and additional ablation, proved superior to pulmonary vein isolation alone for treating persistent atrial fibrillation (AF). This comprehensive approach significantly reduced arrhythmia recurrence at 12 months.

Keywords:
cardiac arrhythmiaethanolhearthumanpulmonary veinstachycardiatherapeutics

More Related Videos

Direct Pressure Monitoring Accurately Predicts Pulmonary Vein Occlusion During Cryoballoon Ablation
11:03

Direct Pressure Monitoring Accurately Predicts Pulmonary Vein Occlusion During Cryoballoon Ablation

Published on: February 26, 2013

19.9K
Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

2.7K

Related Experiment Videos

Last Updated: May 23, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

33.2K
Direct Pressure Monitoring Accurately Predicts Pulmonary Vein Occlusion During Cryoballoon Ablation
11:03

Direct Pressure Monitoring Accurately Predicts Pulmonary Vein Occlusion During Cryoballoon Ablation

Published on: February 26, 2013

19.9K
Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

2.7K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Optimal ablation strategies for persistent atrial fibrillation (AF) beyond pulmonary vein (PV) isolation are not well-defined.
  • Persistent AF management requires advanced techniques to improve patient outcomes.

Purpose of the Study:

  • To compare the efficacy of the Marshall-Plan ablation strategy against pulmonary vein isolation (PVI) alone for persistent AF.
  • To evaluate long-term freedom from arrhythmia after a single ablation procedure.

Main Methods:

  • A prospective, randomized, controlled trial (Marshall-Plan trial) involving patients with symptomatic persistent AF.
  • Two arms: Marshall-Plan (PVI + vein of Marshall ethanol infusion + linear lesions) versus PVI alone.
  • Primary outcome: 1-year freedom from any atrial arrhythmia (>30 seconds) with or without antiarrhythmic medication.

Main Results:

  • The Marshall-Plan strategy achieved 86.4% freedom from arrhythmia, compared to 66.1% with PVI alone (P=0.012) at 12 months.
  • Successful PV isolation was achieved in all patients; vein of Marshall ethanol infusion was completed in 97% of the Marshall-Plan group.
  • High rates of conduction block were achieved for linear lesions in the Marshall-Plan group.

Conclusions:

  • The Marshall-Plan strategy demonstrated significant superiority over PVI alone for treating persistent AF at 12 months.
  • This comprehensive approach offers a promising alternative for managing persistent atrial fibrillation.