How common is the extended temporomandibular joint replacement (eTMJR)? Output data from a single global producer

Area of Science:

• Oral and Maxillofacial Surgery
• Biomaterials Engineering
• Medical Device Technology

Background:

• The use of extended temporomandibular joint replacement (eTMJR) prostheses is rising for managing large segmental mandibular defects involving the temporomandibular joint (TMJ).
• Existing literature highlights adverse events associated with eTMJR, including infection, mechanical failures, and heterotopic bone formation.

Purpose of the Study:

• To compare production volumes of eTMJR devices versus standard temporomandibular joint replacement (TMJR) devices.
• To provide insights into the clinical application and outcomes of eTMJR prostheses.
• To guide clinicians and researchers in optimizing eTMJR as a complex mandibular reconstruction strategy.

Main Methods:

• A cohort study analyzing production data from Stryker/TMJ Concepts.
• Literature review of reported adverse events and clinical applications of eTMJR.

Main Results:

• Extended temporomandibular joint replacement (eTMJR) prostheses constitute 13.5% of all TMJR devices produced.
• Identified adverse events include infection, mechanical failures, and heterotopic bone formation.

Conclusions:

• eTMJR is an emerging option for complex mandibular reconstructions, but careful consideration of adverse events is necessary.
• Future research should focus on device design, materials, regenerative medicine, and predictive tools to improve eTMJR longevity and success.