[Lactation inhibition with various dosages of lisuride--prolactin secretion and effectiveness]

The influence of lisuride in three several dosages (600, 750, and 900 micrograms) was studied on prolactin secretion and inhibition of lactation in 30 normal postpartum patients. 10 normal nursing postpartum patients served as controls. A rebound effect of prolactin secretion was demonstrable following lisuride medication during 10 days. This effect did not occur after a therapy lasting 15 days. 600 micrograms of lisuride daily showed a good inhibition of lactation and suppression of prolactin secretion. Severe side effects could be only observed during lisuride treatment with a dosage of 900 micrograms.