First Description of Simultaneous Sweet Syndrome and Tracheal Stenosis as Extraintestinal Manifestations in a Patient...

Sweet syndrome and tracheal stenosis are very rare extraintestinal manifestations of inflammatory bowel diseases. In this study, we present a patient with ulcerative colitis, who developed Sweet syndrome in combination with an acute tracheal stenosis causing a life-threatening situation requiring admission to the intensive care unit. The patient had an excellent response to intravenous corticosteroids and intravenous infliximab, which had to be switched to vedolizumab after an allergic reaction to infliximab. The patient remained in stable remission with vedolizumab. This is, to our knowledge, the first case reported, in which these very rare extraintestinal manifestations occurred simultaneously.