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Updated: May 5, 2026

Biophysical Characterization of Flagellar Motor Functions
Published on: January 18, 2017
Effect of the background flow on motility-induced phase separation
Soni D Prajapati1, Akshay Bhatnagar2,3, Anupam Gupta1
1Department of Physics, Indian Institute of Technology Hyderabad, Hyderabad 502284, India. agupta@phy.iith.ac.in.
Abstract:
We simulate active Brownian particles (ABPs) with soft-repulsive interactions subjected to a four-roll-mill flow. In the absence of flow, this system exhibits motility-induced phase separation (MIPS). To investigate the interplay between MIPS and flow-induced mixing, we introduce dimensionless parameters: a scaled time, τ, and a scaled speed, V, characterizing the ratio of ABP to fluid time and speed scales, respectively. The parameter space defined by τ and V reveals three distinct ABP distribution regimes. At low speeds, V ≪ 1, flow dominates, leading to a homogeneous mixture. Conversely, at high speeds, V ≫ 1, motility prevails, resulting in MIPS. In the intermediate regime (V ∼ 1), the system's behavior depends on τ. For τ < 1, a moderately mixed homogeneous phase emerges, while for τ > 1, a novel phenomenon, termed flow-induced phase separation (FIPS), arises due to the combined effects of flow topology and ABP motility and size. To characterize these phases, we analyze drift velocity, diffusivity, mean-squared displacement, giant number fluctuations, radial distribution function, and cluster-size distribution.

