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The Cold Spark: A Novel Synergistic Paradigm With Pulsed Field Cryoablation

Leonid Maizels1,2,3, Peter M Kistler4,5,6,7

  • 1The Royal Melbourne Hospital, Melbourne, Australia.

Journal of Cardiovascular Electrophysiology
|May 21, 2025
PubMed
Abstract

No abstract available in PubMed .

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Cryo-electron Microscopy01:28

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...

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