Barriers to clinical genetic testing in movement disorders

Area of Science:

• Neurology
• Genetics
• Clinical Practice

Background:

• The number of known genetic movement disorders and treatments has increased significantly.
• Genetic testing for movement disorders is currently underutilized in clinical settings.
• Understanding barriers to genetic testing is crucial for improving patient care.

Purpose of the Study:

• To explore barriers preventing routine and widespread use of genetic testing for movement disorders.
• To identify factors hindering the integration of genetic testing into clinical practice for movement disorders.

Main Methods:

• This review synthesizes current literature on barriers to genetic testing for movement disorders.
• Analysis of factors including cost, access, knowledge, and discrimination concerns.

Main Results:

• Major barriers include cost, limited insurance, and access to genetic testing and counseling, particularly in low- and middle-income countries.
• Clinician misperceptions, limited knowledge, and concerns about genetic discrimination also impede utilization.
• International studies show large-scale genetic testing and counseling for movement disorders is feasible.

Conclusions:

• Addressing barriers requires concerted action from governments, specialty societies, and health insurance organizations.
• Improving utilization of genetic testing for movement disorders necessitates a multi-level organizational approach.
• Global efforts are needed to enhance access and application of genetic testing in movement disorder management.