Related Experiment Video
Updated: May 22, 2025
08:23
CIRCLE-Seq for Interrogation of Off-Target Gene Editing
Published on: November 1, 2024
452
A Reset for Bioethics: A Statement from the Global Observatory for Genome Editing.
Sheila Jasanoff1, J Benjamin Hurlbut2, Krishanu Saha3
1Harvard Kennedy School, Cambridge, Massachusetts, USA.
The CRISPR Journal
|May 21, 2025
Summary
Global discussions on genome editing require a new approach. We need to broaden deliberation, ensure equitable benefit distribution, and redefine research limits for responsible innovation in life sciences.
Area of Science:
- Bioethics
- Genetics
- Societal Impact of Science
Background:
- Human germline genome editing presents complex ethical and societal challenges.
- Previous approaches to deliberating on emerging technologies have shown limitations.
Purpose of the Study:
- To propose a new framework for governing genome editing technologies.
- To advocate for a more inclusive and comprehensive approach to public deliberation on life sciences innovation.
Main Methods:
- Analysis of shortcomings in prior technology governance models.
- Call for a revised social compact for science and technology.
Main Results:
- Identified need to move beyond a science-first approach.
- Emphasized expanding deliberative scope and re-evaluating innovation's benefits and risks.
Conclusions:
- A new social compact is essential for responsible genome editing governance.
- Acknowledging and addressing the role of science and technology in shaping human life is crucial.
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