Related Experiment Video
Updated: May 22, 2025
08:23
CIRCLE-Seq for Interrogation of Off-Target Gene Editing
Published on: November 1, 2024
452
Moving Therapeutic Genome Editing into Global Clinical Trials and Medicine
Kiran Musunuru1, Fyodor Urnov2
1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
The CRISPR Journal
|May 21, 2025
Abstract:
Moving CRISPR-based therapies from discovery to dosing patients in clinical trials and ultimately to approval involves navigating a challenging terrain of highs and lows. In this interview, physician-scientist Kiran Musunuru and genome editor Fyodor Urnov reflect on the past 20 years of their nonclinical and clinical programs in the field, the current landscape of innovation, and what they see on the horizon.
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