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ELMOD2 Overexpression Predicts Adverse Outcomes and Regulates Tumor Progression in Gliomas

Rui-Chao Li1,2, Chang Liu3, Guo-Jian Wang1

  • 1Department of Histology and Embryology, School of Basic Medicine Science, Guangxi Medical University, Nanning, 530021, China.

Current Medical Science
|May 21, 2025
PubMed
Summary

ELMO domain containing 2 (ELMOD2) is overexpressed in gliomas, correlating with poor prognosis and promoting tumor growth. Knocking down ELMOD2 inhibits glioma cell proliferation and invasion, identifying it as a potential therapeutic target.

Keywords:
Cell cycle regulationELMO domain containing 2GTPase-activating proteinGliomaPrognostic markerTumor progression

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