Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Toluene embryopathy.

J H Hersh, P E Podruch, G Rogers

    The Journal of Pediatrics
    |June 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Exposure to toluene during pregnancy may cause birth defects in infants, including microcephaly and developmental issues. Further research is needed to understand the full impact of prenatal toluene exposure on child development.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Care to Ease the Slope? Differences in Canadian and Californian Medical Assistance in Dying Laws.

    The American journal of bioethics : AJOB·2023
    Same author

    Acute kidney injury: prevention, detection, and management. Summary of updated NICE guidance for adults receiving iodine-based contrast media.

    Clinical radiology·2021
    Same author

    Quality-of-life analysis with intermittent vismodegib regimens in patients with multiple basal cell carcinomas: patient-reported outcomes from the MIKIE study.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2020
    Same author

    To the Editors of the Medical and Physical Journal.

    The Medical and physical journal·2018
    Same author

    B-Vitamin Therapy for Kidney Transplant Recipients Lowers Homocysteine and Improves Selective Cognitive Outcomes in the Randomized FAVORIT Ancillary Cognitive Trial.

    The journal of prevention of Alzheimer's disease·2017
    Same author

    Expansion and further delineation of the SETD5 phenotype leading to global developmental delay, variable dysmorphic features, and reduced penetrance.

    Clinical genetics·2017
    Same journal

    Standardized Mean Differences Reveal Substantial Selection Bias in Post-Reduction Management of Intussusception.

    The Journal of pediatrics·2026
    Same journal

    Parenteral Lipid Dose and Bilirubin Neurotoxicity in Extremely Preterm Infants: A Factorial Randomized Trial.

    The Journal of pediatrics·2026
    Same journal

    Refining Oxygen-Carrying Capacity Metrics in Assessing Mortality Risk from Pneumonia in Children.

    The Journal of pediatrics·2026
    Same journal

    Time-to-Transfer and Hospitalization Duration for Severe Congenital Heart Defects: Implications for Perinatal Regionalization.

    The Journal of pediatrics·2026
    Same journal

    Multimodal neuromonitoring in neonatal hypoxic-ischemic encephalopathy and the association with neurodevelopmental outcomes: A Multicenter Study.

    The Journal of pediatrics·2026
    Same journal

    KP.2-Adapted BNT162b2 COVID-19 Vaccine Uptake and Effectiveness in Children.

    The Journal of pediatrics·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Toxicology

    Background:

    • Prenatal exposure to certain substances can lead to congenital malformations.
    • Toluene is a common industrial solvent with potential neurotoxic effects.

    Observation:

    • Three infants born to mothers with significant prenatal toluene inhalation presented with microcephaly.
    • These infants also exhibited central nervous system dysfunction, craniofacial and limb anomalies, and growth deficiency.

    Findings:

    • The observed malformations share similarities with patterns seen after in utero exposure to alcohol, anticonvulsants, and hyperphenylalaninemia.
    • This suggests a potentially variable and nonspecific teratogenic phenotype associated with toluene exposure.

    Implications:

    Related Experiment Videos

    • Prenatal toluene exposure may represent a risk factor for congenital anomalies and developmental disorders.
    • Infants exposed in utero require careful evaluation and long-term monitoring for developmental outcomes.
    • Further studies are warranted to elucidate the teratogenic potential of toluene and establish clinical guidelines.