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ÆMMamba: An Efficient Medical Segmentation Model With Edge Enhancement.

Xingbo Dong, Bowen Zhou, Chen Yin

    IEEE Journal of Biomedical and Health Informatics
    |May 21, 2025
    PubMed
    Summary
    This summary is machine-generated.

    ÆMMamba, a new framework for medical image segmentation, improves accuracy by effectively modeling long-range dependencies. It achieves state-of-the-art results on multiple datasets for polyp, lung, breast, and brain tumor segmentation.

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    Area of Science:

    • Medical Image Analysis
    • Artificial Intelligence
    • Computer Vision

    Background:

    • Accurate medical image segmentation is vital for clinical applications but challenged by image complexity.
    • Existing methods like CNNs and Vision Transformers have limitations in modeling long-range dependencies efficiently.
    • State Space Models offer potential for efficient long-range dependency modeling.

    Purpose of the Study:

    • To introduce ÆMMamba, a novel multi-scale feature extraction framework for enhanced medical image segmentation.
    • To address the limitations of current models in capturing both local and global image features.
    • To improve segmentation accuracy across diverse medical imaging modalities and datasets.

    Main Methods:

    • Developed ÆMMamba based on the Mamba backbone, incorporating an Efficient Fusion Bridge (EFB) for multi-scale feature fusion.
    • Integrated an Edge-Aware Module (EAM) using Sobel-based edge extraction to enhance low-level features.
    • Utilized a Boundary Sensitive Decoder (BSD) with inverse attention and residual convolutions for complex boundary handling.

    Main Results:

    • ÆMMamba achieved state-of-the-art performance on 8 medical segmentation datasets.
    • Demonstrated superior performance in polyp segmentation (e.g., 72.22 mDice on ETIS) compared to MADGNet and Swin-UMamba.
    • Outperformed H2Former and SwinUnet in lung and breast segmentation (e.g., 84.24 Dice on BUSI, 79.83 on COVID-19 Lung).
    • Achieved high scores on LGG brain MRI segmentation (87.25 mDice, 79.31 mIoU).

    Conclusions:

    • ÆMMamba represents a significant advancement in medical image segmentation, outperforming existing methods.
    • The proposed framework effectively integrates multi-scale features and boundary information for robust segmentation.
    • ÆMMamba shows great potential for various clinical applications requiring precise image segmentation.