The NeVa stent-retriever - a single-centre real-world experience

Area of Science:

• Neurology
• Interventional Neuroradiology
• Vascular Medicine

Background:

• Mechanical thrombectomy (MT) using stent retrievers is a key treatment for acute ischemic stroke (AIS) from large vessel occlusion (LVO).
• First-pass effect (FPE) is a critical predictor of successful outcomes in LVO AIS patients undergoing MT.

Purpose of the Study:

• To evaluate the real-world efficacy of the NeVa stent retriever in achieving FPE and successful recanalization in LVO AIS patients.
• To analyze factors associated with FPE and functional outcomes in a prospectively maintained registry.

Main Methods:

• Independent central reader review of 89 consecutive LVO AIS patients treated with the NeVa stent retriever.
• Analysis of procedural parameters including device length, use of Balloon Guide Catheter (BGC), and distal aspiration.
• Assessment of first-pass effect (eTICI ≥2c) and final recanalization (eTICI ≥2c).

Main Results:

• FPE (eTICI ≥2c) was achieved in 57% of patients; modified FPE (eTICI ≥2b) in 65.1%.
• Final successful recanalization (eTICI ≥2c) was achieved in 87% of cases.
• Good functional outcome (mRS ≤2) was observed in 40% of patients.

Conclusions:

• The NeVa stent-retriever demonstrates a high rate of FPE and final recanalization in a real-world setting.
• The use of longer NeVa devices, BGC, and proximal aspiration may optimize FPE.
• These findings support the effectiveness of the NeVa stent retriever for LVO AIS treatment.