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Thrombotic thrombocytopenic purpura in pregnancy: response to plasma manipulations

J D Upshaw, T J Reidy, K Groshart

    Southern Medical Journal
    |June 1, 1985
    PubMed

    We present three cases of thrombotic thrombocytopenic purpura (TTP) and one case of the hemolytic-uremic syndrome (HUS) occurring during pregnancy. All patients and their offspring survived, and none of the infants had TTP or HUS. Plasma manipulations (exchange and infusions) were the effective therapeutic measures in all patients. The most significant complication of therapy was posttransfusion hepatitis, which occurred in three patients, and from which recovery was complete.

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