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Updated: May 23, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Photoinduced Direct Formylation of Anilines: Aerobic Oxidation Using an Odd Alternate Hydrocarbon Phenalenyl-Based
Vishali Pathania1, Gaurav Kumar1, Sudipta Raha Roy1
1Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Abstract:
We have introduced a sustainable approach for the photoinduced oxidative formylation of N,N-dimethylanilines using a phenalenyl-based photocatalyst. The methodology exhibits tolerance to a variety of electron-donating and -withdrawing groups as well as to diverse functional groups, specifically offering a selective and efficient pathway for the N-formylation. Using visible light, this photochemical technique proves to be an environmentally friendly, scalable, and milder alternative strategy. The mechanistic insights were gained through a series of spectroscopic techniques, including electron paramagnetic resonance, steady-state fluorescence, and fluorescence lifetime studies. Postfunctionalization was also completed and has the potential to be used in various applications.
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