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Updated: Jun 14, 2025

Motor and Hippocampal Dependent Spatial Learning and Reference Memory Assessment in a Transgenic Rat Model of Alzheimer's Disease with Stroke
Published on: March 22, 2016
A place for place cells in post-stroke cognitive impairment
1Department of Psychology, Binghamton University, SUNY, Binghamton, NY 13902, USA.
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In a recent study, Heiser et al. showed that hippocampal place cell stability and spatial encoding were disrupted in mice after brain-wide microstrokes. These findings suggest that hippocampal neurons are particularly vulnerable to dysfunction after stroke, even in the absence of local lesions. They also highlight the potential to improve place cell stability and rescue post-stroke memory function.
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