Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Parkinson's Disease: Overview

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Functional Neurological Disorder.

Seminars in neurology·2026

Same author

The "Hallett Sign" of Functional Jerky Movement Disorder.

Movement disorders : official journal of the Movement Disorder Society·2026

Same author

Neuropsychiatric Treatment in Functional Neurological Disorder: Foundations and Future.

Seminars in neurology·2026

Same author

Psychiatric and behavioural side effects of antiseizure medications in epilepsy.

Journal of neurology·2025

Same author

Education Research: Evaluation of Epilepsy Surgery Education in Epilepsy and Clinical Neurophysiology Fellowship Programs.

Neurology. Education·2025

Same author

Comparative analysis of postpartum depression incidence in patients with epilepsy on levetiracetam or lamotrigine monotherapy during pregnancy.

Epilepsy & behavior : E&B·2025

Same journal

Contemporary surgical strategies for resection of intracranial gliomas.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

FGF17 synergistically targets neuronal survival and oligodendrogenesis to restore stroke deficits.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

Sotagliflozin improves cognitive deficits and attenuates neuroinflammation of Alzheimer's disease.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

Neurological complications of current and emerging CAR-T cell therapies.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

Hemodynamics Beyond Ischemic Zone Underlies Early Neurological Deterioration in Minor Stroke with Large Vessel Occlusion.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

Nervonic acid and the long arc of therapeutic hope in X-linked adrenoleukodystrophy.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 23, 2025

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

Functional neurological disorder: Practical management.

Barbara A Dworetzky¹, Gaston Baslet²

¹Brigham and Women's Hospital, Mass General Brigham, Department of Neurology, Harvard Medical School, Boston, USA.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics

|May 21, 2025

Summary

This summary is machine-generated.

Functional Neurological Disorder (FND) is a common, disabling neurological condition. Research shows brain network abnormalities are key, and diagnosis requires specific criteria for effective management.

Keywords:

Conversion Dissociative FND Functional neurological disorder Psychogenic

More Related Videos

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

Related Experiment Videos

Last Updated: May 23, 2025

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy

Published on: January 11, 2016

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Author Spotlight: Enhancing Upper Limb Rehabilitation in Stroke Patients Through Advanced Robotic and Neuromodulation Technologies

Published on: October 11, 2024

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation

Published on: February 23, 2020

Area of Science:

Neurology
Neuroscience
Clinical Medicine

Background:

Functional Neurological Disorder (FND) is a prevalent and disabling condition across various clinical settings.
It presents with diverse subtypes, most commonly seizure and motor/movement disorders.
FND is associated with significant healthcare utilization, costs, and often leads to chronic disability.

Purpose of the Study:

To provide a practical overview of diagnosing and managing Functional Neurological Disorder (FND).
To highlight the role of brain network abnormalities in FND pathophysiology.
To emphasize evidence-based treatments and multidisciplinary care approaches.

Main Methods:

Review of current research on FND pathophysiology, particularly brain network activity.
Analysis of diagnostic criteria, including common pitfalls in clinical history taking.
Synthesis of expert consensus recommendations and evidence-based treatment strategies.

Main Results:

Abnormalities in brain network activity are implicated in the pathophysiology of FND.
Accurate diagnosis relies on positive criteria and careful clinical assessment.
Evidence-based treatments and multidisciplinary teams are crucial for optimal patient outcomes.

Conclusions:

Effective management of FND requires a thorough understanding of its pathophysiology and diagnostic nuances.
Multidisciplinary collaboration is essential for improving outcomes in patients with FND.
Further research is needed to advance the care and understanding of this complex disorder.